DETERMINANTS OF FIRST & SECOND PHASE INSULIN SECRETION (FPIS, SPIS) IN HEALTHY ADOLESCENTS
نویسندگان
چکیده
منابع مشابه
Second-phase insulin secretion gets cool.
STIMULUS-SECRETION COUPLING of insulin is a highly orchestrated process initiated by the uptake of glucose by pancreatic -cells culminating with the fusion of insulin vesicles with the plasma membrane and release of insulin into the extracellular space. A hallmark feature of stimulus-secretion coupling is the biphasic nature of insulin secretion following an elevation in plasma glucose levels (...
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AIM The present study evaluated the relative influence of body mass index (BMI) on insulin resistance (IR), first-phase insulin secretion (FPIS), second-phase insulin secretion (SPIS), and glucose effectiveness (GE) at a fixed fasting plasma glucose level in an older ethnic Chinese population. METHODS In total, 265 individuals aged 60 years with a fasting plasma glucose level of 5.56 mmol/L w...
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Previous work has shown increased insulin sensitivity, increased hepatic insulin clearance and lower postprandial insulin responses following treatment with resistant starch, a type of dietary fibre. The objective of this study was to further explore the effects of resistant starch on insulin secretion. Twelve overweight (BMI 28.2±0.4 kg/m(2)) individuals participated in this randomized, subjec...
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Aims. There are two phases of insulin secretion, the first (FPIS) and second phase (SPIS). In this study, we built equations to predict FPIS with metabolic syndrome (MetS) components and fasting plasma insulin (FPI). Methods. Totally, 186 participants were enrolled. 75% of participants were randomly selected as the study group to build equations. The remaining 25% of participants were selected ...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1993
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-199305001-00423